Epithelial Pathways in Choroid Plexus Electrolyte Transport

Epithelial pathways in choroid plexus electrolyte transport.

A stable intraventricular milieu is crucial for maintaining normal neuronal function. The choroid plexus epithelium produces the cerebrospinal fluid and in doing so influences the chemical composition of the interstitial fluid of the brain. Here, we review the molecular pathways involved in transport of the electrolytes Na+, K+, Cl-, and HCO3(-)across the choroid plexus epithelium.

Transport of methotrexate by the choroid plexus.

Methotrexate-3H was accumulated in vitro against a con centration gradient by the rabbit choroid plexus. This accumu lation was energy dependent, inhibited by metabolic inhibitors, and exhibited self-saturation and competitive inhibition. Several folie acid analogs with a 4-amino group were inhibitors of this accumulation, while folie and folinic acid, compounds which do not contain a 4-amino g...

Transport across the choroid plexus epithelium.

The choroid plexus epithelium is a secretory epithelium par excellence. However, this is perhaps not the most prominent reason for the massive interest in this modest-sized tissue residing inside the brain ventricles. Most likely, the dominant reason for extensive studies of the choroid plexus is the identification of this epithelium as the source of the majority of intraventricular cerebrospin...

I-45: Choroid Plexus Cyst

CPCs are a relatively common finding during the second trimester sonography. when a choroid plexus cyst is identified, the presence of structural malformation and other sonographic markers of aneuploidy should be assessed with a detailed fetal anatomic survey performed by an experienced person. if no other sonographic abnormalities are present, the CPC is considered isolated. given the consider...

Cl- channel expression in choroid plexus epithelial cells.